Born in Pembroke, Ontario, Canada, Green grew up in suburban Ottawa. While attending Algonquin College he had a radio show on the University of Ottawa's campus radio station, CHUO, before getting his first series on an Ottawa community channel, Rogers Television. It was later picked up by Canada's Comedy Network. It was after his popularity in Canada that MTV gave Green his own show in the United States. He would later go on to write and star in full length Hollywood feature films.
In 2003, Green returned with a nightly talk show on MTV called The New Tom Green Show. Although the show had its own quirks (including a regular segment where Humplick was sent to sleep in various uncomfortable places) it was more of a conventional talk show and generally less confrontational than Green's earlier work. It started with strong ratings and was a hit with many critics, and Green was compared in print to a young Johnny Carson or David Letterman. Nevertheless, it was abruptly cancelled by MTV a few months after its premiere due to MTV deciding that wasn't the direction they wanted to go in.
In recent years, Green has tried to put some of his more controversial material behind him and become a more mainstream entertainer. Currently, Green is a recurring contributor to The Tonight Show with Jay Leno; he has done many segments where he travels across America looking for "interesting people", typically bringing the most colorful person with him back to the studio. In these segments, the focus is more on the odd behavior of the interviewees, with Green generally playing the straight man. Green has also attempted to build his teen and child audience with more wholesome material. In 2005, Green starred in a children's TV movie, Bob the Butler, and he has made guest appearances on various kid shows. Green has one film scheduled for release in 2006. Furthermore, Green is editing a new film which he also directed and starred in tentatively titled Prankstar. No further details about the film have yet been released.
On June 5, 2006, ManiaTV.com announced they had formed a partnership with Green to host a live call-in show for their internet broadcast. The show is called Tom Green Live. The show takes place in his own living room in the Hollywood Hills overlooking the San Fernando Valley. The show started on June 15, 2006 at 11 p.m. EST. The show airs every Monday - Friday night (and also whenever Tom feels like going on the air, such as Monday Funday and Freestyle Fridays), with re-runs playing throughout the week, including original Tom Green Show footage. Guests on the show have included stars such as Val Kilmer, Andrew Dice Clay, Xzibit, skateboarder Tony Hawk, stuntman Steve-O, former TRL host and talk show host Carson Daly, guitarist Dave Navarro, actor Crispin Glover, Digg.com founder Kevin Rose, and comedic musician "Weird Al" Yankovic. For lack of an established term, Tom often refers to his live streaming broadcast as "Web-o-vision." He also jokingly says he is broadcasting to "the national Internet."